Nano Silver Particles Impregnated Guided Tissue Regeneration Membranes

Use of Collagen membranes for bone regeneration is a very effective surgical modality in dentistry. However, bacterial contamination of the wound site and the membranes are known to significantly compromise the desired outcomes.

If exposed, long term use of antibiotics to prevent the bacterial contamination is not favourable/advised for long periods. Use of collagen membranes impregnated with nano-silver particles have a superior efficacy against bacterial colonisation on membranes than impregnated antibiotics. Silver nanoparticles can exert superior activity by better contact with microorganisms resulting in a higher interaction with bacterial membranes and DNA.

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Normal and Nanosilver impregnated collagen membranes.

Curetted and degranulated intrabony defect.

Placement of nanosilver impregnated membrane over the defect.

Final Suturing.

Mean membrane adherence score of (a) F. nucleatum; (b) P. gingivalis; (c) S. mutans; (d) A. actinomycetemcomitans. NS-GTR-5, NS-GTR-10, and NS-GTR-15 are membranes impregnated with 5,10 & 15nm nanosilver solutions. GTR-C is plain GTR membranes and MET-GTR is metronidazole impregnated membranes (Click on the picture to view the original study).

Nanosilver membranes show higher bone fill over untreated membranes as well (Dr. B. Raghavendra Goud “Clinical and Microbiological Evaluation of Nano Silver Particles Impregnated Guided Tissue Regeneration Membrane in Intra-Osseous Defects –A Randomized Control Trial” Dissertation submitted to KNR University of Health Sciences, Warangal)

Nano Silver Particles Impregnated Guided Tissue Regeneration Membranes

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